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Effect of lipid composition of liposomes on their clearance from the blood stream and accumulation in the mouse liver

โœ Scribed by S. A. Burkhanov; V. P. Torchilin

Publisher
Springer US
Year
1987
Tongue
English
Weight
245 KB
Volume
103
Category
Article
ISSN
0007-4888

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Annamycin (Ann) is a non-cross-resistant lipophilic anthracycline antibiotic optimally suited for liposome delivery. We studied how vesicle size and presence of phospholipids with a high phase transition temperature and monosialoganglioside (GM I) in the liposome bilayers affect the pharmacokinetics