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Effect of itraconazole on cerivastatin pharmacokinetics

✍ Scribed by T. Kantola; K. T. Kivistö; P. J. Neuvonen


Publisher
Springer
Year
1999
Tongue
English
Weight
113 KB
Volume
54
Category
Article
ISSN
0031-6970

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Effect of itraconazole on the pharmacoki
✍ Kazuyo Nishihara; Junko Hibino; Hajime Kotaki; Yasufumi Sawada; Tatsuji Iga 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 2 views

The effect of itraconazole (ITZ) on the pharmacokinetics of digoxin (DGX) was investigated in guinea pigs. The plasma concentrations of DGX in guinea pigs following treatment with ITZ (20 mg/kg intraperitoneally (i.p.)) after intravenous (i.v.) administration of DGX (0.125 mg/kg) were significantly