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Effect of iron and ascorbate on cyclosporine-induced oxidative damage of kidney mitochondria and microsomes

✍ Scribed by Suk Ha Lee; Young Chul Yoon; Yoon Young Jang; Jin Ho Song; Eun Sook Han; Chung Soo Lee

Book ID
118770922
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
464 KB
Volume
43
Category
Article
ISSN
1043-6618

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The inhibition by citrinin (CTN) of lipid peroxidation of mitochondria, sub-mitochondrial particles (SMP) and microsomes was studied. This eect was reversed by the presence of high concentrations of Fe 3 (0 . 4 and 0 . 5 mM), suggesting chelation of the mycotoxin with iron or interference in the red