High-conductance potassium channels have been studied in inside-out patches excised from proteoliposomes reconstituted from giant liposomes and rat brain synaptosomes. Acid pH in the medium reduced single channel current amplitude and increased the mean open probability and the frequency of channel
✦ LIBER ✦
Effect of intracellular pH on potassium conductance in liver
✍ Scribed by Robert M. Henderson; Birgit Krumpholz; James L. Boyer; Jürg Graf
- Book ID
- 104819425
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 231 KB
- Volume
- 412
- Category
- Article
- ISSN
- 0031-6768
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H3%l (specific activity 9.2 pCi/mg of Cl), [14C] urea (specific activity 55 mCi/mmol), [14C]NaSCN (specific activity 19 mCi/mmol), "NaC1 (specific activity 1.100 mCi/mg, and 86RbC1 (specific activity 5 mCi/mg) were obtained from The Radiochemical Centre (Amersham, England). MES, Tris, Hepes, furosem