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Effect of indomethacin on the cyclic AMP-dependent protein kinase

✍ Scribed by R. Edgardo Catalán; Maria D. Aragones; Ana.M. Martinez; Manuel Armijo; Manuel Piña


Book ID
115876268
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
233 KB
Volume
63
Category
Article
ISSN
0014-2999

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Extracts obtained from rat hepatocytes incubated with saline, glucagon or insulin were electrophoresed on polyacrylamide gels and then assayed for cyclic (3H)AMP binding capacity. Analysis of the binding patterns demonstrated that glucagon dissociated a holoenzyme of cyclic AMP-dependent protein kin