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Effect of ignoring genotype-environment interaction on segregation analysis of quantitative traits

✍ Scribed by Dr. Laurence Tiret; Laurent Abel; Roger Rakotovao

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 294 KB
Volume: 10
Category: Article
ISSN: 0741-0395
DOI: 10.1002/gepi.1370100642

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✦ Synopsis

Abstract

Thirty replicates of 200 nuclear families (6 members each) were generated under three GxE interaction models. Segregation analyses of these data were performed using a regressive model taking into account an interaction effect or not. Results showed that ignoring the GxE interaction markedly decreased the power for accepting a major gene and led to serious bias in parameter estimates. © 1993 Wiley‐Liss, Inc.

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