Effect of hypoxia on the expression of i
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Qian-Qian Luo; Dan Wang; Min-Yan Yu; Li Zhu
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Article
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2011
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John Wiley and Sons
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English
β 540 KB
Iron is essential for many biological processes, including oxygen delivery, and its supply is tightly regulated. Iron regulatory proteins (IRPs, IRP1 and IRP2) are master regulators of cellular iron metabolism. Hypoxia triggers a broad range of gene responses that are primarily mediated by hypoxia-i