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Effect of hypoxia and hypoxia/reoxygenation on proteoglycan metabolism by vascular smooth muscle cells

✍ Scribed by Julio E. Figueroa; Zhuo Tao; Theodore G. Sarphie; Frank W. Smart; D.Luke Glancy; Parakat Vijayagopal

Book ID: 119438298
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 611 KB
Volume: 143
Category: Article
ISSN: 0021-9150
DOI: 10.1016/s0021-9150(98)00292-5

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## Abstract Previous work from our laboratory has shown that heparin inhibits the proliferation of vascular smooth muscle cells in vivo and in vitro. The mechanism of action of this glycosaminoglycan is unknown. In this communication, we have examined the antiproliferative effect of heparin on smoo