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Effect of hypophysectomy on persistence of methylated purines in rat liver deoxyribonucleic acid after administration of dimethylnitrosamine

โœ Scribed by Anthony E. Pegg; Georgiana Hui; Kenneth J. Rogers


Book ID
115746956
Publisher
Elsevier Science
Year
1978
Weight
481 KB
Volume
520
Category
Article
ISSN
0005-2787

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Pharmacokinetics and therapeutic effects of oltipraz were evaluated after consecutive (once per day at 30 mg/kg/day for 7 and 14 days) or intermittent (once per week at 100 mg/kg/week for 1-3 weeks) oral administration to rats with liver cirrhosis induced by dimethylnitrosamine. The AUC of oltipraz