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Effect of Hydroxypropyl-β-cyclodextrin on the Central Stimulant Activity of (−)-Ephedrine and an Oxazolidine Prodrug in Rats

✍ Scribed by R.B Walker; V.N Dholakia; K.L Brasfield; R Bakhtiar


Book ID
114233678
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
428 KB
Volume
30
Category
Article
ISSN
0306-3623

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## Molecular complexes of an oxazolidine prodrug of (-)-ephedrine, cis-2-(4-methoxyphenyl)-3,4-dimethyl- 5-phenyloxazolidine, with α-, β-, dimethyl-β-(DM-β-) and hydroxypropl-β-(HP-β-) cyclodextrins (CDs) were examined using ionspray mass spectrometry. The results suggest, under our experimental c