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EFFECT OF HYDROGEN SULPHIDE ON β-AMYLOID-INDUCED DAMAGE IN PC12 CELLS

✍ Scribed by Xiao-Qing Tang; Chun-Tao Yang; Jing Chen; Wei-Lan Yin; Shao-Wen Tian; Bi Hu; Jian-qiang Feng; Yuan-Jian Li

Book ID
108940168
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
248 KB
Volume
0
Category
Article
ISSN
0305-1870

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## Abstract Amyloid β peptide (Aβ) is implicated in the pathogenesis of Alzheimer's disease (AD). The peptide is toxic to neurons, possibly by causing initial synaptic dysfunction and neuronal membrane dystrophy, promoted by increased cellular Ca^2+^. Calpain (Ca^2+^‐dependent protease) and caspase