Effect of histamine and stress on the gastric mucosal Ca2+content during the development of gastric ulcers
✍ Scribed by L. L. Grechishkin; K. Riethling; U. Zelck; U. Karnstedt
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1979
- Tongue
- English
- Weight
- 377 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1420-908X
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Neurotensin (NT) and bombesin, which are heterogeneously distributed in both brain and gastrointestinal tissue of several mammalian species, inhibit the formation of stress-induced gastric ulcers in rats. Many other endogeneous neuropeptides have also been reported to be present in brain and gastroi
## Summary A proximal gastric vagotomy (PGV) prevented experimental duodenal ulcers in rats for only 5 days and thereafter all rats developed duodenal ulceration. In sham-operated rats the mean stimulated gastric acid output was 186 μmol/60 min. Immediately following a PGV there was a significant d