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Effect of HER2/neu Expression on Survival in Non–Small-Cell Lung Cancer

✍ Scribed by Vijaya Korrapati; Maryanne Gaffney; Lisbeth G. Larsson; Lucio Di Nunno; Mark Riggs; Robert S. Beissner; John J. Rinehart; Frank E. Mott


Book ID
115076035
Publisher
CIG Media Group, LP.
Year
2001
Tongue
English
Weight
844 KB
Volume
2
Category
Article
ISSN
1525-7304

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HER2 is an erbB/HER type 1 tyrosine kinase receptor that is frequently over-expressed in malignant epithelial tumours. Herceptin, a humanised mouse monoclonal antibody to HER2, is proven therapeutically in the management of metastatic breast cancer, significantly prolonging survival when combined wi