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Effect of heat shock on RNA polymerase activities in Chinese hamster ovary cells

✍ Scribed by M. Caizergues-Ferrer; G. Bouche; D. Banville; F. Amalric


Book ID
118314347
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
620 KB
Volume
97
Category
Article
ISSN
0006-291X

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The possible mechanism for heat protection by the protein synthesis inhibitor histidinol was investigated in CHO cells. Histidinol (HST, 5 mM), an analogue of the essential amino acid L-histidine, added for 2 hr before and during heating at 43"C, protected cells from killing at 43Β°C. Treatment with