Effect of glucocorticoids on the binding of atrial natriuretic peptide to endothelial cells
โ Scribed by Katherine L. Lanier-Smith; Mark G. Currie
- Book ID
- 115886547
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 628 KB
- Volume
- 178
- Category
- Article
- ISSN
- 0014-2999
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to brain microvessels, the resultant increase in cGMP (Charbrier et al., 1987(Charbrier et al., , 1988;; Steardo and Nathanson, 19871, and the 5,000-fold greater surface area of the brain microvessels as compared to regions not protected by the BBB (Pardridge et al., 1986) suggest a physiologically
Atrial natriuretic peptide (ANP) is a fluid-regulating peptide hormone that promotes vasorelaxation, natriuresis, and diuresis. The mechanisms for the release of ANP and for its clearance from the circulation play important roles in modulating its biological effects. Recently, we have reported that