✦ LIBER ✦

Characterization of atrial natriuretic peptide receptors in brain microvessel endothelial cells

✍ Scribed by Peggy A. Whitson; M. Helen Huls; Clarence F. Sams

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 1016 KB
Volume: 146
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041460107

No coin nor oath required. For personal study only.

✦ Synopsis

to brain microvessels, the resultant increase in cGMP (Charbrier et al., 1987(Charbrier et al., , 1988;; Steardo and Nathanson, 19871, and the 5,000-fold greater surface area of the brain microvessels as compared to regions not protected by the BBB (Pardridge et al., 1986) suggest a physiologically significant role for circulating ANP in the fluid homeostasis of the brain.

Receptors for ANP have been identified in several cell and tissue types, including endothelial cells

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