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Effect of glucocorticoid excess on the cortisol/cortisone ratio

✍ Scribed by Jörg Dötsch; Helmuth G Dörr; Günter K Stalla; Wolfgang G Sippell

Book ID
117213397
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
160 KB
Volume
66
Category
Article
ISSN
0039-128X

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## Abstract The measurement of the urinary free cortisol–cortisone ratio has been reported to be a sensitive indicator of renal 11 __β__‐hydroxysteroid dehydrogenase type 2 (11 __β__‐HSD 2) activity. This converts biologically active cortisol to inactive cortisone. A decrease in its activity (e.g.