Effect of Freund's complete adjuvant in the precancer period on chemical carcinogenesis
โ Scribed by A. I. Volegov
- Publisher
- Springer US
- Year
- 1971
- Tongue
- English
- Weight
- 211 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0007-4888
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## Hamsters were inoculated with varied regimens of adenovirus type 12 and complete Freund's adjuvanr neonatally, and/or during the latent period preceding appearance of tumors. Virus andlor adjuvant were administered either separately or together as emulsions. In all instances adjuvant treatment
Complete Freund's adjuvant was shown to greatly stimulate viral oncogenesis both in the case of polyoma virus in niico and in the case q f Rous sarcoma virus in rats. Tumours appeared in 74 of CCS7BRIMv mice inkcred when newborn with polyoma virusadjuvant emulsion, whereas control rxiciJ injectpd wi