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Effect of free fatty acids and phospholipids on growth of and product formation by recombinant baby hamster kidney (rBHK) and Chinese hamster ovary (rCHO) cells in culture

โœ Scribed by Schmid, G.; Zilg, H.; Eberhard, U.; Johannsen, R.


Book ID
123116983
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
659 KB
Volume
17
Category
Article
ISSN
0168-1656

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To investigate the effect of culture pH in the range of 6.85 -7.80 on cell growth and erythropoietin (EPO) production at 32.5 and 37.0jC, serum-free suspension cultures of recombinant CHO cells (rCHO) were performed in a bioreactor with pH control. Lowering culture temperature from 37.0 to 32.5jC su