𝔖 Bobbio Scriptorium
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Effect of food on vinorelbine pharmacokinetics

Book ID
120861821
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
138 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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The pharmacokinetics of vinorelbine has been investigated by a new HPLC method in 8 cancer patients receiving 8 weekly doses (30 mg.m-2) administered by brief infusion (15 min). The plasma concentration-time curves showed a tri-exponential decay with a long terminal half-life (44.7 h) and a high vol