Effect of fluoxetine on weight reduction in obese patients
โ Scribed by M Afkhami-Ardekani; H Sedghi
- Publisher
- Association of Clinical Biochemistry of India
- Year
- 2005
- Tongue
- English
- Weight
- 270 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0970-1915
No coin nor oath required. For personal study only.
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The effect of dexfenfluramine (dF) on body weight, blood pressure and noradrenergic activity were studied in 30 obese hypertensive patients randomly divided into two groups and treated for 3 months either with dF (30 mg daily; 16 subjects) or placebo (Pl; 14 subjects). 11 patients from the dF group
Fluoxetine, a serotonin reuptake inhibitor, reduced the food intake and body weight of both normal mice and viable yellow obese mice fed ad libitum. Fluoxetine was given at 10 mg/ kg, i.p., daily for 10 days or fed in the diet at a concentration of 0.04% for 21 days. In both experiments, mice did no