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Effect of exercise on urate crystal-induced inflammation in canine joints

✍ Scribed by Carlos A. Agudelo; Dr. H. Ralph Schumacher; Paulding Phelps

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
574 KB
Volume
15
Category
Article
ISSN
0004-3591

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✦ Synopsis

Abstract

The effect of joint motion on one model of experimental articular inflammation, the acute arthritis produced by injection of urate crystals into canine knees, has been examined. Each increased amount of joint motion produced larger effusions, higher leukocyte counts, more severe histologic evidence of polymorphonuclear leukocyte infiltration and increased leakage of intravenously injected carbon from synovial vessels. Clearance of xenon from the joint was markedly accentuated by joint motion.

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