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Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer

✍ Scribed by Nohelia Cajas-Salazar; William W Au; Joseph B Zwischenberger; Carlos H Sierra-Torres; Salama A Salama; Scott K Alpard; Stephen K Tyring


Book ID
114135611
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
111 KB
Volume
145
Category
Article
ISSN
0165-4608

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Microsomal epoxide hydrolase polymorphis
✍ Hua Zhao; Margaret R. Spitz; Karin M. Gwyn; Xifeng Wu πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 91 KB

## Abstract Microsomal epoxide hydrolase (mEPHX) is a critical metabolic enzyme involved in the activation and subsequent detoxification of specific tobacco carcinogens. __mEPHX__ harbors polymorphisms in exon 3 and exon 4 that modulate enzymatic activity. The exon 3 polymorphism decreases mEPHX me