Effect of epidermal growth factor on the synthetic activity of human fibroblasts
โ Scribed by Huey, Jeff; Sampath Narayanan, A.; Jones, Karen; Page, R.C.
- Book ID
- 123051073
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 375 KB
- Volume
- 632
- Category
- Article
- ISSN
- 0304-4165
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To study the relationship between androgen metabolism and the pathogenesis of benign prostatic hypertrophy, we purified a growth factor from benign hyperplastic tissue of human prostates and assayed the proliferative responses of human fetal prostatic fibroblasts to the purified growth factor (hPGF)
## Abstract The effect of human epidermal growth factor (hEGF), a 5,400 molecular weight polypeptide isolated from human urine, on the growth of human foreskin fibroblasts (HF cells) was studied by measuring cell numbers and the incorporation of labeled thymidine. The addition of hEGF to HF cells g