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Effect of Drug Solubility on Polymer Hydration and Drug Dissolution from Polyethylene Oxide (PEO) Matrix Tablets

โœ Scribed by Hongtao Li; Robert J. Hardy; Xiaochen Gu


Book ID
111767811
Publisher
Springer US
Year
2008
Tongue
English
Weight
250 KB
Volume
9
Category
Article
ISSN
1530-9932

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โœ Jari Pajander; Ossi Korhonen; Maria Laamanen; Eeva-Leena Ryynรคnen; Ian Grimsey; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 394 KB ๐Ÿ‘ 2 views

The aim of this study was to determine, whether interactions between a drug and hydrophobic polymer matrix are present, and if so, how they affect the drug release. In addition, the most important formulation parameters, for example porosity or structure of the tablet, which have the greatest impact