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Effect of Drug Active Substance Particles on Wet Granulation Process

✍ Scribed by Z. Belohlav; L. Brenková; J. Hanika; P. Durdil; P. Rapek; V. Tomasek

Book ID
111765354
Publisher
Institution of Chemical Engineers
Year
2007
Tongue
English
Weight
408 KB
Volume
85
Category
Article
ISSN
0263-8762

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The objective is to provide mechanistic understanding of a preferred wet granulation process that a binder is added in a dry state. Blends of CaCO(3) and binders were prepared and used as model systems, and they were exposed to either 96% RH (rubbery/solution state) or 60% RH (glassy state) at room