A mechanistic understanding of the over-granulation problem during high shear wet granulation (HSWG) process can guide efficient development of robust formulation and manufacturing process. Using microcrystalline cellulose (MCC) as a model compound, we demonstrate that size enlargement is an importa
β¦ LIBER β¦
Effect of primary particle size on granule growth and endpoint determination in high-shear wet granulation
β Scribed by Michael B. Mackaplow; Lawrence A. Rosen; James N. Michaels
- Book ID
- 114080573
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 956 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0032-5910
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