Effect of dipicolinate, a chelator of zinc, on bone protein synthesis in tissue culture: The essential role of zinc
โ Scribed by Yamaguchi Masayoshi; Matsui Ryukichi
- Book ID
- 115781277
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 660 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0006-2952
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The present investigation was undertaken to clarify the in oitro effect of zinc on bone metabolism in tissue culture. Calvaria were removed from weanling rats (3-week-old males) and cultured for periods up to 96 hr in Dulbecco's Modified Eagle Medium (high glucose, 4500 mg/dl) supplemented with anti
Parenterally administered zinc markedly increased the incorporation of I 4C-cystine and 6 5 Zn into a low mo1ecula.r weight zinc binding protein (ZnBP) isolated from liver cytoplasm of rats fed an adequate amount of zinc. This zinc load significantly increased the zinc content in the liver. The incr