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Effect of dimethindene, an antihistaminic drug, on the transmembrane potentials of mammalian myocardium

✍ Scribed by J. Mészáros; E. Hlavacsek-Póka; J. Szegi


Publisher
Springer
Year
1983
Tongue
English
Weight
354 KB
Volume
39
Category
Article
ISSN
1420-682X

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently