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Effect of diltiazem and tetrodotoxin on development of anoxic contracture of the guinea pig myocardium

✍ Scribed by V. J. Gendviliené; R. A. Kudzmaité; J. A. Jurevičius


Publisher
Springer US
Year
1988
Tongue
English
Weight
203 KB
Volume
105
Category
Article
ISSN
0007-4888

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently