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Effect of detergents on in vitro 7α-hydroxycholesterol formation by rat liver microsomes

✍ Scribed by Ajit Sanghvi; Enrico Grassi; Candace Bartman; Warren F. Diven

Book ID
112773504
Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
422 KB
Volume
17
Category
Article
ISSN
0024-4201

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In a search for enzymes involved in the formation of bile acids from 27-hydroxycholesterol in humans, the metabolism of this and other side-chain oxygenated steroids was studied in human liver microsomes and mitochondria. The microsomal fraction contained enzyme(s) catalyzing 7a-hydroxylation of 27-