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Bile Acid Synthesis in Isolated Rat Liver Cells : The Effect of 7α-Hydroxycholesterol

✍ Scribed by Kathleen M. BOTHAM; Geoffrey J. BECKETT; Iain W. PERCY-ROBB; George S. BOYD

Book ID
115118605
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
586 KB
Volume
103
Category
Article
ISSN
1432-1327

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In a search for enzymes involved in the formation of bile acids from 27-hydroxycholesterol in humans, the metabolism of this and other side-chain oxygenated steroids was studied in human liver microsomes and mitochondria. The microsomal fraction contained enzyme(s) catalyzing 7a-hydroxylation of 27-