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Effect of cyclooxygenase-2 expression in colon cancer cells on chemotaxis of neutrophils and macrophages

โœ Scribed by Tsujii, M.; Kawano, S.; Tsuji, S.; Takei, Y.; Nagai, H.; Sawaoka, H.; Murata, H.; Kawai, N.; Hori, M.; DuBois, R.N.

Book ID
122097438
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
179 KB
Volume
114
Category
Article
ISSN
0016-5085

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Cyclooxygenase-2 (COX-2) over-expression is critically involved in tumor formation. Intracellular pH (pHi) has been shown to be alkaline in cancer cells, and to be an important trigger for cell proliferation. This study therefore analyzed the relationship between pHi and COX-2 expression. HRT-18 and