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Effect of cyanide on the reaction of nitroprusside with hemoglobin: relevance to cyanide interference with the biological activity of nitroprusside

✍ Scribed by Wilcox, Dean E.; Kruszyna, Harriet; Kruszyna, Robert; Smith, Roger P.


Book ID
127161391
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
782 KB
Volume
3
Category
Article
ISSN
0893-228X

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Protein labeling by reductive methylatio
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have demonstrated that reductive methylation with labeled formaldehyde and NaCNBH, provides a simple method for specifically labeling the amino groups of proteins using extremely mild reaction conditions. However, cyanide, which is one of the products of the reaction, reduces labeling efficiency by