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Effect of concurrently coadministered drugs on the pharmacokinetic/pharmacodynamic profile of centchroman, a nonsteroidal oral contraceptive, in rats

✍ Scribed by Vipul Kumar; Jawahar Lal; Man Mohan Singh; Ram Chandra Gupta


Book ID
116381355
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
275 KB
Volume
74
Category
Article
ISSN
0010-7824

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The effect of omeprazole on oral and intravenous (iv) RS-methadone pharmacokinetics and pharmacodynamics was studied in awake, freely moving rats, which were divided in four groups: oral RS-methadone (3 mg/kg) was given (a) to a control group (CO(oral)) (n = 65) and (b) to an omeprazole pretreated g