Effect of cocultivation of the levels of spontaneous and induced sister chromatid exchanges in chinese hamster cells

✍ Scribed by Giuseppe Rainaldi; Fulvio Luccini; Tullio Mariani

• Publisher: John Wiley and Sons
• Year: 1982
• Tongue: English
• Weight: 344 KB
• Volume: 112
• Category: Article
• ISSN: 0021-9541
• DOI: 10.1002/jcp.1041120218

✦ Synopsis

Abstract

The level of sister chromatid exchanges, both spontaneous and induced by UV light or ethylmethanesulphonate (EMS), in Chinese hamster V79/AP4 cell line, is partially reduced upon cocultivation with human cells. Normal and xeroderma pigmentosum (XP) cells are equally effective. On the basis of these observations, cocultivation may represent a good tool for investigating the SCE's formation processes.