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Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells

✍ Scribed by Maria Uhl; Sonja Ecker; Fekadu Kassie; Evelyne Lhoste; Asima Chakraborty; Georges Mohn; Siegfried Knasmüller

Publisher: Springer-Verlag
Year: 2003
Tongue: English
Weight: 240 KB
Volume: 77
Category: Article
ISSN: 0340-5761
DOI: 10.1007/s00204-003-0469-4

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## Abstract Quercetin, 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (a), and okadaic acid are found in various foods and have been shown to have mutagenic or promoter‐like activity. The effects of these three compounds on the transmission of the inactive × chromosome were examined in MST‐C6