Effect of cerebral ischemia on acute convulsions and chronic epileptogenesis
โ Scribed by M. N. Karpova; I. Yu. Abrosimov; G. N. Kryzhanovskii
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 284 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0007-4888
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The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion. All rats had 24 h ischemia, and were divided into three groups (ten rats per group). Groups 1 and 2 received 1.0 and 3.2 mg/kg nilvadipine s.c. r
## Abstract The effect of acute exposure to lead acetate (LA)/lead nitrate (LN) on onset and severity of convulsions induced by a low dose of picrotoxin was examined in rats. Both LA and LN reduced the time of onset and exacerbated the severity of convulsions, with a resultant high lethality. On co