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Effect of trimetazidine on cerebral metabolism during acute ischemia complicated by hypoxia

โœ Scribed by A. V. Smirnov; I. V. Zarubina; B. I. Krivoruchko; O. P. Mironova


Publisher
Springer US
Year
2000
Tongue
English
Weight
234 KB
Volume
129
Category
Article
ISSN
0007-4888

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Astrocytes were incubated under normoxic or hypoxic conditions in Dulbecco's minimum essential medium containing [2-13C]acetate, unlabeled glucose and in some cases orotic acid, an intermediate in pyrimidine biosynthesis. After 12 hr the medium was replaced by fresh medium without drug and incubatio