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Effect of cell-cycle inhibition on synthesis of steroidal alkaloids bySolanum aviculareplant cells

✍ Scribed by Yunxian Mak; Pauline M. Doran

Publisher
Springer Netherlands
Year
1993
Tongue
English
Weight
228 KB
Volume
15
Category
Article
ISSN
0141-5492

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✦ Synopsis

Addition of 40 mg 1-1 hydroxyurea to Solanum aviculare cultures resulted in complete inhibition of growth and an increase in the levels of steroidal alkaloids in the biomass. These results demonstrate that solasodine synthesis and growth can be uncoupled, and suggest that steroidal-alkaloid production can be significantly enhanced by inhibiting growth at high cell density. Treatment with 1 rng 1-1 abscisic acid had a negligible effect on growth and product synthesis.

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