𝔖 Bobbio Scriptorium
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Effect of cationic groups on the adhesivity of peritoneal macrophages to polymeric beads

✍ Scribed by K. Smetana; M. Jelínková; J. Vacík; M. Novák

Publisher
Springer
Year
1995
Tongue
English
Weight
689 KB
Volume
6
Category
Article
ISSN
0957-4530

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✦ Synopsis

This study demonstrates the adhesion of macrophages to polymer beads from a copolymer of hydroxyethyl methacrylate and dimethyl aminoethyl methacrylate intraperitoneally injected into the rat. Dimethyl aminoethyl methacrylate exhibited a stimulatory effect on macrophage adhesion 5 h after injection of the beads. Electron microscopy demonstrated protein adsorption on the surface of the beads. Protein fibres between the cell surface and beads were observed. The experimental system used minimizes the influence of tissue damage at macrophage recognition of polymers. This method seems to be suitable for short-term investigation of macrophage-polymer interaction.

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