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Effect of catechol-O-methyltransferase Val(108/158)Met polymorphism on antidepressant efficacy of fluvoxamine

✍ Scribed by F. Benedetti; S. Dallaspezia; C. Colombo; C. Lorenzi; A. Pirovano; E. Smeraldi

Book ID
118440017
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
174 KB
Volume
25
Category
Article
ISSN
0924-9338

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## Abstract ## Objective Genetic polymorphisms of the noradrenergic pathway can be factors to predict the effect of antidepressants when their pharmacological mechanisms of action include the noradrenergic system. The purpose of the present study was to determine whether the tyrosine hydroxylase (