Amorphous calcium phosphate coatings were produced by pulsed laser deposition from targets of nonstoichiometric hydroxyapatite (Ca/P Γ 1.70) at a low substrate temperature of 300 ΠC. They were heated in air at different temperatures: 300, 450, 525 and 650 ΠC. Chemical and structural analyses of thes
Effect of calcium phosphate (Ca-P) coatings on trabecular bone response: A histological study
β Scribed by Caulier, H. ;van Der Waerden, J. P. C. M. ;Paquay, Y. C. G. J. ;Wolke, J. G. C. ;Kalk, W. ;Naert, I. ;Jansen, J. A.
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 871 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0021-9304
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β¦ Synopsis
The trabecular bone response to noncoated and fluorapatite (FA), hydroxyapatite (HA), and hydroxyapatite heattreated (HAHT) plasma-sprayed coated implants was investigated in a goat animal model. Forty-eight cylindrical implants were inserted into the trabecular bone of the lateral and medial femoral condyles of twelve goats according to a split plot design. After an implantation period of twelve weeks, the bone-implant interface was evaluated histologically. Quantitative histomorphometrical measurements demonstrated a significant difference in bone contact between implants inserted in the lateral and medial condyles. In addition, a significant difference in bone apposition was observed between the coated and the uncoated implants. Finally, all Ca-P coatings showed reduction in coating thickness. Measurements revealed that FA and HAHT showed less reduction in coating thickness than HA coating. Despite the coating reduction, the bone remained in close contact with the implant surface. 0 1995 John Wiley & Sons, Inc.
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Changes occurring at the surface of a calcium phosphate coating when in contact with osteoblasts versus those in acellular solutions were analyzed. The coating studied is one with a well-documented extensive effect on shortterm bone growth stimulation. Precipitates associated with original crystals
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