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Effect of Caffeine on Acetaminophen Hepatotoxicity in Cultured Hepatocytes Treated with Ethanol and Isopentanol

โœ Scribed by Keith DiPetrillo; Sheryl Wood; Vsevolod Kostrubsky; Kathryn Chatfield; Jenna Bement; Steven Wrighton; Elizabeth Jeffery; Peter Sinclair; Jacqueline Sinclair

Book ID
112268696
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
92 KB
Volume
185
Category
Article
ISSN
0041-008X

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Acetaminophen (APAP) with or without ascorbyl stearate (AS) or ascorbyl palmitate (AP) was administered by gavage to male Swiss-Webster mice at a dose of 600 mg/kg for each chemical. The biochemical markers of hepatotoxicity, serum transaminases (serum glutamate pyruvate transaminase [SGPT], serum g