Effect of buffer constituents on the determination of therapeutic proteins by capillary electrophoresis
β Scribed by Norberto A. Guzman; John Moschera; Khurshid Iqbal; A. Waseem Malick
- Book ID
- 118328668
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 751 KB
- Volume
- 608
- Category
- Article
- ISSN
- 1873-3778
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Adequate buffering is of vital importance in capillary electrophoresis. Inadequate buffering may result in severe pH drift and erratic separation behavior. The aim of this work was to study the effects of buffering and buffer replenishment on the repeatability of absolute migration times and on the
## Abstract The performance of the most common and also some other less common CE buffers has been tested for the p__K__~a~ determination of several types of compounds (pyridine, amines, and phenols). The selected buffers cover a pH ranging from 3.7 to 11.8. Whereas some buffers, like acetic acid/a
## Abstract Solute migration in capillary electrophoresis is the sum of the molecularly specific electrophoretic mobility and the electricβfieldβinduced solvent flow (electroosmosis). This solvent flow is an important component of capillary electrophoresis and has been linked to resolution and auto