This study investigated the effects of the short-term administration of propranolol on gastric blood perfusion in cirrhotic patients with portal hypertensive gastropathy. Portal hypertensive gastropathy is a common cause of nonvariceal bleeding in cirrhosis, which is associated with increased gastri
Effect of bolus injection and continuous infusion of somatostatin on gastric perfusion in cirrhotic patients with portal-hypertensive gastropathy
✍ Scribed by JuliáN Panés; Josep M. Piqué; Josep M. Bordas; Maria Casadevall; Josep Terés; Jaime Bosch; Juan Rodés
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 648 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0270-9139
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📜 SIMILAR VOLUMES
## AND JCAN RODES~ Gastric mucosal perfusion is increased in portalhypertensive gastropathy, and this may contribute to gastric bleeding from these lesions. Therefore drugs reducing gastric mucosal perfusion may be beneficial in the treatment of overt bleeding from portal-hypertensive gastropathy.
The present double-blind study was aimed at investigating the hemodynamic and humoral effects of somatostatin or placebo in patients with cirrhosis. Patients were randomly assigned to receive either an injection of 250 pg of somatostatin followed by a constant infusion of somatostatin at 250 pg/h (n