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Effect of biochanin A on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells

✍ Scribed by Eun Hee Han; Ji Young Kim; Hye Gwang Jeong

Publisher
Springer
Year
2006
Tongue
English
Weight
995 KB
Volume
29
Category
Article
ISSN
0253-6269

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## Abstract Carcinogenic polycyclic aromatic hydrocarbons(a) form DNA adducts via a complex metabolic activation pathway that includes cytochrome P450(a) 1A1, whereas intermediate metabolites can be detoxified by conjugation through pathways including glutathione s‐transferase M1 (GSTM1). PAH‐DNA a