𝔖 Bobbio Scriptorium
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Effect of bioactive glass particle size on osseous regeneration

✍ Scribed by Ducheyne, Paul

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
99 KB
Volume
46
Category
Article
ISSN
0021-9304

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✦ Synopsis

Recently D. Wheeler et al. published the paper "Effect of bioactive glass particle size on osseous regeneration of cancellous defects." 1 In this publication, the authors discussed in vivo findings generally useful to interpret the effect of bioactive glass (BG) on bone tissue. Specifically, the authors also set out to "histologically and biomechanically compare the 45S5 bioactive glass, produced by US Biomaterials in a wide particle range (USB), to the narrower particle range glass produced by Orthovita (OV)."

The authors are commended for clearly observing that BG, a material first described in the early seventies, 2 can resorb and is not necessarily just surface active. The paper documents an extensive reduction of the size parameters measured for the two particulate materials as a function of implantation time. It used to be that BG was held to be a "bioactive material," dis-

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