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Effect of bile acid structure on the feed-back regulation of bile acid synthesis in man: Studies on cholesterol 7α-hydroxylation

✍ Scribed by Bastu, E.; Gokulu, S.; Celik, C.; Bulgurcuoglu, S.; Dural, O.; Yasa, C.

Book ID
122452444
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
73 KB
Volume
5
Category
Article
ISSN
0168-8278

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✍ Douglas M. Heuman; Z. Reno Vlahcevic; Marsha L. Bailey; Phillip B. Hylemon 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac