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Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital-treated rats

✍ Scribed by Xuan Zhao; Jun-Jie Zhang; Xin Wang; Xiu-Yun Bu; Ya-Qing Lou; Guo-Liang Zhang

Book ID: 116313822
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 328 KB
Volume: 62
Category: Article
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2007.02.009

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## Abstract Four β‐glycosides of flavonoligan silybin, i.e. silybin β‐galactoside, silybin β‐glucoside, silybin β‐maltoside, silybin β‐lactoside were synthesized in order to improve silybin water solubility and bioavailability (Křen et al., J Chem Soc, Perkin Trans 1, 2467–2474, 1997). The presente